کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7625741 | 1494557 | 2014 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Grain sorghum whole kernel oil lowers plasma and liver cholesterol in male hamsters with minimal wax involvement
ترجمه فارسی عنوان
روغن کل دانه سورگوم دانه ای باعث کاهش کلسترول پلاسما و کبد در همسترهای نر و ماده می شود
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
The lipid fraction of the grain sorghum whole kernel (GS-WK) (i.e., phytosterol rich oil or policosanol rich wax) responsible for lowering cholesterol in hamsters fed the crude lipid (wax + oil) was determined. As expected, hamsters fed an atherogenic diet for a four week period presented with higher plasma non-HDL plasma and liver esterified cholesterol than those on the low fat diet. However, the atherogenic diet containing 5% (w/w) oil significantly lowered non-HDL plasma and liver cholesterol. Although the 5% wax supplement did not affect either plasma or liver cholesterol, excreted neutral sterol and bile acid were slightly higher than produced by the atherogenic diet. Still, cholesterol excretion negatively correlated with liver cholesterol concentration (r = â0.681, p < 0.001) across diets with the oil fraction producing the greatest impact. These combined results indicate that oil plays the most significant role in modulating cholesterol, most likely by inhibiting absorption, but subtle interactions by the wax may be involved. However, the sorghum oil would be the most potent component to serve as a possible heart health ingredient in functional foods.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Functional Foods - Volume 7, March 2014, Pages 709-718
Journal: Journal of Functional Foods - Volume 7, March 2014, Pages 709-718
نویسندگان
Bo Hyun Lee, Timothy P. Carr, Curtis L. Weller, Susan Cuppett, Ismail M. Dweikat, Vicki Schlegel,