Development of a SPE-UHPLC-MS/MS methodology for the determination of non-steroidal anti-inflammatory and analgesic pharmaceuticals in seawater

- A method for the analysis of NSAIDs and analgesic pharmaceuticals in seawater was developed.
- The method is based on SPE and UHPLC-MS/MS.
- All pharmaceuticals were detected in seawater during bathing season.
- Ibuprofen metabolites appeared at higher concentrations that ibuprofen.