Isolation, LC-MS/MS and 2D-NMR characterization of alkaline degradants of tenofovir disoproxil fumarate

- Describes preparative LC isolation and NMR based characterization.
- Optimized HPLC method to separate tenofovir disoproxil fumarate and degradants.
- LC-MS/MS data for structure conformations.
- Structure interpretation of degradants using 1H, 13C, DEPT, COSY and HSQC.