In vitro bioassays to screen for endocrine active pharmaceuticals in surface and waste waters

- Applicability of in vitro bioassays to monitor E2 and EE2 in surface waters.
- A proposal for their implementation in the context of the Water Framework Directive.
- Resulting in a cost-reduction of “high end” analytical measurements of E2 and EE2.
- Presentation of a EEQ-based risk assessment framework for AA-EQS compliance check.