کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7630268 1645359 2015 32 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Optimization and validation of a chiral GC-MS method for the determination of free d-amino acids ratio in human urine: Application to a Gestational Diabetes Mellitus study
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Optimization and validation of a chiral GC-MS method for the determination of free d-amino acids ratio in human urine: Application to a Gestational Diabetes Mellitus study
چکیده انگلیسی

- A GC-MS method was optimized and validated for determination of d-AAs ratio in urine.
- The sample preparation was based on SCX-SPE with only 1 mL of urine.
- Fourteen pairs of AAs were separated.
- The method was applied to a Gestational Diabetes Mellitus study with pregnant women (n = 20 control; n = 20 GDM).
- d-Phe ratio was found statistically significant higher in urine of GDM women.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pharmaceutical and Biomedical Analysis - Volume 107, 25 March 2015, Pages 480-487
نویسندگان
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