Comprehensive quantitative analysis of Shuang-Huang-Lian oral liquid using UHPLC-Q-TOF-MS and HPLC-ELSD

- Commercial Shuang-Huang-Lian liquor (SHL) was quantitatively analyzed.
- Fifteen small molecules were determined using UHPLC-Q-TOF-MS.
- Three carbohydrates were determined using HPLC-ELSD.
- The total determined contents reached up to 78% of the dry weight of SHL.
- This study provides an efficient quantitation method to assess the quality of SHL.