Ultra-high-pressure liquid chromatography tandem mass spectrometry determination of hallucinogenic drugs in hair of psychedelic plants and mushrooms consumers

- An UHPLC-MS/MS analysis of mescaline, N,N-dimethyltryptamine, psilocin, psilocybin, salvinorin A has been developed and validated.
- It was applied to hair of consumers of peyote cacti, psilocybe mushrooms, Salvia divinorum or ayahuasca.
- A rapid and simple digestion of the keratin matrix with M3 reagent has been applied.
- Excellent results for determination of hallucinogenic drugs in hair of consumers.