Stereochemical and conformational study on fenoterol by ECD spectroscopy and TD-DFT calculations

- Fenoterol derivatives display stereoselective activity as β2-AR agonists.
- A full stereochemical characterization of fenoterol derivatives is crucial.
- A combined ECD and TD-DFT analysis was performed on fenoterol stereoisomers.
- TD-DFT calculations confirm the stereochemistry of fenoterol stereoisomers.
- DFT geometries reveal different conformational patterns among diastereomers.