Application of LA-ICP-MS as a rapid tool for analysis of elemental impurities in active pharmaceutical ingredients

- LA-ICP-MS method was developed for trace elements in the pharmaceutical substance.
- Laboratory-made matrix calibration standards were prepared and evaluated.
- Trace elements content was monitored in drugs according Pharmacopeia requirements.
- Suitability and stability of laboratory-made standards for LA-ICP-MS were studied.
- Fast LA-ICP-MS method for solid samples was developed.