Comparison of Raman spectroscopy vs. high performance liquid chromatography for quality control of complex therapeutic objects: Model of elastomeric portable pumps filled with a fluorouracil solution

- We compare the performance of HPLC to Raman spectroscopy.
- The two methods were validated for trueness, precision and accuracy.
- There is a statistical correlation between Raman spectroscopy and HPLC.
- Raman spectroscopy is effective for analytical quality control of 5-fluorouracil.
- Raman spectroscopy contributes to protect caregivers and their working environment.