Determination of monoamine and amino acid neurotransmitters and their metabolites in rat brain samples by UFLC-MS/MS for the study of the sedative-hypnotic effects observed during treatment with S. chinensis

- Simultaneous determination of eight neurotransmitters in rat brain.
- The total analysis time was 11.0 min.
- LLOQ were 8.0, 16, 4.0, 4.0, 4.0, 4.0, 8.0 and 8.0 ng mL−1 for the analytes.
- S. chinensis changed the brain neurotransmitters for sedative-hypnotic effect.