Analytics of the therapeutic peptide aviptadil by sheathless CE-MS and comparison with nanoRP-HPLC-MS

- Therapeutic peptide analysis by a sheathless CE-ESI-MS system.
- Supplementary nature of CE-MS and nanoRP-HPLC-MS demonstrated.
- Sensitivity of CE-MS was 500-fold higher than determined for nanoLC-MS.
- Matrix effects in nanoLC modifies artificially ratio of oxidized to non-oxidized peptide species.