Pharmacokinetic characterization of oxymatrine and matrine in rats after oral administration of radix Sophorae tonkinensis extract and oxymatrine by sensitive and robust UPLC-MS/MS method

- Establishment of a more sensitive and robust UPLC-MS/MS method.
- PK of OMT and MT at low dose in rats.
- Comparison of PK behavior between radix Sophorae tonkinensis extract and pure OMT.