Myélolipome extra surrénalien de la rate : Ã propos de 2 cas

Myelolipoma is a lesion arising in the adrenal glands or in various extra-adrenal sites. Only one human case developing in the spleen has been published in the literature. We report two such exceptional cases discovered in two women aged 65 and 67 years, presenting with splenomegaly. Both spleens showed a round mass constituted by red pulp containing nests of extra-medullar haematopoiesis and adipose tissue resembling bone marrow tissue. In addition, Emh developed in the surrounding red pulp. Erythroblasts and granulocytic cells at different stages of normal maturation and a few megakaryocytes were observed, without blasts. We consider the relationship with extra-adrenal myelolipoma and the differential diagnosis with non neoplastic and neoplastic Emh.