کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7658400 | 1495103 | 2010 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
La résistance aux antituberculeux
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Anti-tuberculosis drug resistance remains a challenging matter in numerous countries, including countries close to France in Eastern Europa. Consequently, anti-tuberculosis drug resistance surveillance remains essential. Because of the epidemiological importance of multi-drug-resistant, even extensively-drug-resistant tuberculosis (XDR-TB), it is necessary to test not only the first-line drugs but also the new, second-line drugs. Resistances are not transferable but are the consequence of mutations. Resistance mutations are detected by genotypic techniques, which are now available for an increasing number of drugs. The rapidity of the molecular diagnosis is particularly useful for patients with treatment failure, allowing a quick adaptation of the treatment whilst also lowering tuberculosis transmission. However, all resistance mechanisms have not been yet elucidated. The risk of false negative cannot be underestimated with molecular tests and the proportion method must still be performed.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Revue Francophone des Laboratoires - Volume 2010, Issue 422, May 2010, Pages 43-50
Journal: Revue Francophone des Laboratoires - Volume 2010, Issue 422, May 2010, Pages 43-50
نویسندگان
Jeanne Maugein, Audrey Chemoul,