Effects of ionic liquid and nanogold particles on high-performance liquid chromatography-electrochemical detection and their application in highly efficient separation and sensitive analysis of five phenolic acids in Xuebijing injection

► A novel high performance HPLC-ECD system by applying ILs and Nanogold as additives. ► The influence of the additives on the separation and detection of the phenolic acids. ► The optimized conditions were used in the pharmacokinetics of Xuebijing injection.