Multimethod quantification of Ag+ release from nanosilver

► We report on three complementary methods for the quantification of Ag+ in a suspension of nanosilver. ► Ion-exchange technique was optimized to measure free Ag+. ► Single particle ICP-MS and ultrafiltration were used to quantify dissolved Ag. ► When diluted, silver nanoparticles will dissolve, implying that nAg will not persist in the environment.