Simple and sensitive aptasensor based on quantum dot-coated silica nanospheres and the gold screen-printed electrode

► Fabricated an electrochemical aptasensor with simplicity and high sensitivity. ► Gold nanoparticles were electrodeposited onto a screen-printed electrode. ► Bound QDs were dissolved in an acid-dissolution step and were detected. ► Nanoparticles may be favorable for amplifying electrochemical signals. ► The screen-printed electrode was useful for the large fabrication of the aptasensor.