Combined voltammetric and spectroscopic analysis of small molecule-biopolymer interactions: The levodopa and serum albumin system

► Voltammetric and fluorescence data matrices were combined. ► MCR-ALS was applied to resolve the expanded data matrix. ► Levodopamine-BSA complex is likely to be unfolded during the interaction. ► New previously unobtainable information was extracted by chemometrics.