Blood matrix effects for male and female Wistar rats, in simultaneous HPLC-UV determination of riparin I and III from Aniba riparia (Nees) Mez. (Lauraceae)

► Bioanalytical methods for riparin I and III. ► Centrifugation, time and the extraction solvent used for liquid-liquid extraction. ► Recovery differences for riparin I and III with respect to the sex of the animal. ► Critical influence of matrix effects on the simultaneous recovery of riparin I and III.