Grafting of norfloxacin imprinted polymeric membranes on silica surface for the selective solid-phase extraction of fluoroquinolones in fish samples

► A norfloxacin imprinted polymeric membrane was immobilized on a porous silica-gel support. ► The structural characteristics and adsorption properties of the MIP-Silica were investigated. ► The MISPE procedure was optimized to separate and detect three fluoroquinolone residues in fish.