New heterobimetallic ferrocenyl derivatives: Evaluation of their potential as prospective agents against trypanosomatid parasites and Mycobacterium tuberculosis

Ferrocenyl compounds with tropolone co-ligands showed improved activities on Trypanosoma brucei and selectivities towards the pathogen in respect to the ligands. Compounds were active on Leishmania infantum and Mycobacterium tuberculosis but poorly selective. Interference with the thiol-redox homeostasis of T. brucei was not detected but DNA could be a target.98