Photolabile ruthenium complexes to cage and release a highly cytotoxic anticancer agent

Ruthenium (II) complexes with the anticancer agent CHS-828 {N-[6-(4-chlorophenoxy)hexyl]-N′-cyano-N″-4-pyridyl guanidine} as a ligand are stable in the dark and accumulate in tumour cells at high concentrations. Irradiation of the cells leads to release of CHS-828 and cell death.58