Divergent assembly mechanisms of the manganese/iron cofactors in R2lox and R2c proteins

The heterobinuclear Mn/Fe cofactor in two ferritin-like proteins, the small subunit (R2) of class Ic ribonucleotide reductase (R2c) and the R2-like ligand-binding oxidase (R2lox), is assembled via divergent pathways.109