Thermodynamics of the formation of Ag(I)-mediated azole base pairs in DNA duplexes

The specific binding of Ag(I) ions to DNA duplexes containing imidazole:imidazole or triazole:triazole mispairs in various sequence contexts was probed by isothermal titration calorimetry, yielding a quantitative insight into the thermodynamics of the formation of these artificial Ag(I)-mediated base pairs.186