Cytotoxic activity, DNA damage, cellular uptake, apoptosis and western blot analysis of ruthenium(II) polypyridyl complex against human lung decarcinoma A549 cell

A new Ru(II) complex [Ru(dmp)2(pddppn)](ClO4)2Ru1 was synthesized and characterized. The cytotoxicity, apoptosis, cellular uptake, comet assay, cell cycle arrest, ROS, mitochondrial membrane potential, western blot analysis were investigated.