Vanadium(IV/V) complexes of Triapine and related thiosemicarbazones: Synthesis, solution equilibrium and bioactivity

Solution stability of vanadium(IV/V) complexes of Triapine and its terminally dimethylated derivatives were determined. The most stable complexes were synthesized in solid phase and tested against cancer cell lines. Complexes of salicylaldehyde thiosemicarbazone were also studied in comparison and displayed higher stability.