Synthesis of biocompatible polymeric nano-capsules based on calcium carbonate: A potential cisplatin delivery system

An efficient polymeric drug delivery system based on novel synthetic nanosized CaCO3 is reported that both efficiently loads the widespread anticancer drug cisplatin and controls its release. Optimal loading results were obtained with layer by layer self-assembled polyelectrolyte nanocapsules, which showed a cytotoxic activity comparable to free cisplatin.143