Synthesis, structure and urease inhibition studies of Schiff base copper(II) complexes with planar four-coordinate copper(II) centers

Seven new copper(II) complexes of Schiff bases were synthesized and structurally characterized. Inhibition of jack bean urease by all the obtained copper(II) complexes with planar four-coordinate copper(II) centers was evaluated. A docking analysis via a DOCK program supports their potent inhibitory activities.