Alkynyl β-sheet peptidomimetics retain their anti-parallel sheet conformation when coordinated to tungsten

Peptide derivatives of 2-amino-2′-carboxydiphenylacetylene, which adopt anti-parallel β-sheet conformations in solution, form mono-alkyne complexes when reacted with W(CO)3(dmtc)2. The peptide retains a β-sheet structure in the complex.100