Synthesis, characterization and in vitro biological evaluation of [Ru(η6-arene)(N,N)Cl]PF6 compounds using the natural products arenes methylisoeugenol and anethole

Five new organometallic Ru(II) compounds with the natural ligands methylisoeugenol or anethole were synthesized, fully characterized and biologically evaluated. The in vitro cytotoxicity measurements showed that compounds IX and X were as cytotoxic as carboplatin, which is a commercial drug, against the three human tumor cell lines studied.90