Design, synthesis and anticancer evaluation of 1H-pyrazolo[3,4-d]pyrimidine derivatives as potent EGFRWT and EGFRT790M inhibitors and apoptosis inducers

Design, synthesis and anticancer evaluation of 1H-pyrazolo[3,4-d]pyrimidine derivatives as potent EGFRWT and EGFRT790M inhibitors and apoptosis inducers

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic Chemistry - Volume 80, October 2018, Pages 375-395

Ahmed A. Gaber, Ashraf H. Bayoumi, Ahmed M. El-morsy, Farag F. Sherbiny, Ahmed B.M. Mehany, Ibrahim H. Eissa,