Macrocyclic MEK1/2 inhibitor with efficacy in a mouse model of cardiomyopathy caused by lamin A/C gene mutation

Macrocyclic MEK1/2 inhibitor with efficacy in a mouse model of cardiomyopathy caused by lamin A/C gene mutation

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry - Volume 25, Issue 3, 1 February 2017, Pages 1004-1013

Wei Wu, Mahendra D. Chordia, Barry P. Hart, E. Sathyajith Kumarasinghe, Min K. Ji, Ajay Bhargava, Michael W. Lawlor, Ji-Yeon Shin, Fusako Sera, Shunichi Homma, Antoine Muchir, Uday R. Khire, Howard J. Worman,