Discovery of N-aryl-N′-pyrimidin-4-yl ureas as irreversible L858R/T790M mutant selective epidermal growth factor receptor inhibitors

Discovery of N-aryl-N′-pyrimidin-4-yl ureas as irreversible L858R/T790M mutant selective epidermal growth factor receptor inhibitors

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 28, Issue 7, 15 April 2018, Pages 1257-1261

Fusheng Zhou, Liang Zhang, Yunzhou Jin, Wei Liu, Pengfei Cheng, Xiangyu He, Jing Xie, Sida Shen, Jing Lei, Haixia Ji, Yi Hu, Yingtao Liu, Yumin Cui, Qiang Lv, Jiong Lan,