Lipopolysaccharide based oral nanocarriers for the improvement of bioavailability and anticancer efficacy of curcumin

- We prepared curcumin loaded lipopolysaccharide nanocarriers (C-LPNCs).
- LPNCs showed diffusion-controlled release of curcumin.
- LPNCs showed enhanced oral bioavailability of curcumin.
- C-LPNCs demonstrated higher cytotoxicity than pure curcumin.
- C-LPNCs showed markedly enhanced in vivo anticancer efficacy as well as survival rate.