کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7793546 1500659 2014 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
In vitro and in vivo antioxidant activities of polysaccharide purified from aloe vera (Aloe barbadensis) gel
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
In vitro and in vivo antioxidant activities of polysaccharide purified from aloe vera (Aloe barbadensis) gel
چکیده انگلیسی
The in vitro and in vivo antioxidant potentials of a polysaccharide isolated from aloe vera gel were investigated. Enzymatic extracts were prepared from aloe vera gel by using ten digestive enzymes including five carbohydrases and five proteases. Among them, the highest yield was obtained with the Viscozyme extract and the same extract showed the best radical scavenging activity. An active polysaccharide was purified from the Viscozyme extract using ethanol-added separation and anion exchange chromatography. Purified aloe vera polysaccharide (APS) strongly scavenged radicals including DPPH, hydroxyl and alkyl radicals. In addition, APS showed a protective effect against AAPH-induced oxidative stress and cell death in Vero cells as well as in the in vivo zebrafish model. In this study, it is proved that both the in vitro and in vivo antioxidant potentials of APS could be further utilized in relevant industrial applications.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Polymers - Volume 99, 2 January 2014, Pages 365-371
نویسندگان
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