Synthesis of fused 3-amino-1,2,4-triazoles via sequential addition of aryl hydrazines to isothiocyanates and I2-mediated cyclodesulfurization

The features of the I2-mediated 3-amino-1,2,4-triazole synthesis process includes easy accessibility of substrates, no use of transition metals, mild reaction conditions, simple operation, and efficient and scalable synthesis.190