کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7840172 | 1505863 | 2018 | 27 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Porous GdAlO3:Â Cr3+, Sm3+ drug carrier for real-time long afterglow and magnetic resonance dual-mode imaging
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی تئوریک و عملی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Here, a kind of porous nanoparticles GdAlO3:Cr3+, Sm3+ (GAO:Cr,Sm) which own magnetic resonance and long persistent luminescent properties have been synthesized. The spherical morphology and narrow size distribution would allow the GAO:Cr,Sm nanoparticles to be utilised as a drug carrier and the drug release results indicate that the GAO:Cr,Sm drug carriers have an excellent drug sustained properties. Applying the Cr3+ and Sm3+ coped with gadolinium aluminate as the NIR persistent luminescence center and the energy transfer resonance from Gd3+ to Cr3+, these nanoparticles exhibit excellent NIR persistent luminescence at 732â¯nm under the UV irradiation of 254â¯nm and it can persist for about half an hour. In addition, they possess a longitudinal relaxivity (r1) value of 4.75â¯mMâ1 sâ1, which means that these nanoparticles could be applied for MR imaging as contrast agents. Carboxymethyl Chitosan was modified on the surface of GAO:Cr,Sm nanoparticles to make them owning excellent biocompatibility and low toxicity and these nanoparticles were successful to realize in vivo imaging. Hence, the well-defined nanoprobes of GAO:Cr,Sm exhibit great potential in biomedicine as trackable drug carriers and in vivo imaging agent due to the dual-model imaging property.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Luminescence - Volume 199, July 2018, Pages 363-371
Journal: Journal of Luminescence - Volume 199, July 2018, Pages 363-371
نویسندگان
Jinlei Li, Chengcheng Wang, Junpeng Shi, Penghui Li, Zhenfeng Yu, Hongwu Zhang,