کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7840205 1505865 2018 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Differential recognition and quantification of HSA and BSA based on two red-NIR fluorescent probes
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی تئوریک و عملی
پیش نمایش صفحه اول مقاله
Differential recognition and quantification of HSA and BSA based on two red-NIR fluorescent probes
چکیده انگلیسی
Two red-NIR fluorescence probes, BI-FPI and NTPS-FPI, were developed for the differentiable recognition of HSA and BSA. BI-FPI showed the remarkable selectivity and high sensitivity toward HSA over BSA. BI-FPI located within site I of HSA, which mainly depended on the hydrophobic residues and π-π interaction. The linear response of the fluorescence gave a low detection limit (0.01 μM, 0.66 mg/L) to HSA. On the contrary, NTPS-FPI exhibited a significant selectivity to BSA. It docked into the interface between subdomains II and IIIA of BSA with strong hydrogen bonding interaction, and the quantitative detection limit was 0.03 μM (2.04 mg/L).228
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Luminescence - Volume 197, May 2018, Pages 193-199
نویسندگان
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