Improved osteoblasts growth on osteomimetic hydroxyapatite/BaTiO3 composites with aligned lamellar porous structure

Aligned porous structure of HA/BaTiO3 piezoelectric composites prepared by ice-templating method was similar to the lamellar Haversian system in bone tissue. When co-cultured with human osteosarcoma cells (MG63), porous HA/BaTiO3 composites exhibited remarkable biological activity in promoting proliferation, differentiation and adhesion of MG63 cells.187