کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7869627 1509169 2015 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Electrochemical determination of hydrochlorothiazide and folic acid in real samples using a modified graphene oxide sheet paste electrode
ترجمه فارسی عنوان
تعیین الکتروشیمیایی هیدروکلروتیازید و اسید فولیک در نمونه های واقعی با استفاده از یک الکترود ورق اکسید گرافین اصلاح شده
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد بیومتریال
چکیده انگلیسی
A new ferrocene-derivative compound, 2-chlorobenzoyl ferrocene, was synthesized and used to construct a modified graphene oxide sheet paste electrode. The electrooxidation of hydrochlorothiazide at the surface of the modified electrode was studied. Under optimized conditions, the square wave voltammetric (SWV) peak current of hydrochlorothiazide increased linearly with hydrochlorothiazide concentration in the range of 5.0 × 10− 8 to 2.0 × 10− 4 M and a detection limit of 20.0 nM was obtained for hydrochlorothiazide. The diffusion coefficient and kinetic parameters (such as electron transfer coefficient and the heterogeneous rate constant) for hydrochlorothiazide oxidation were also determined. The prepared modified electrode exhibits a very good resolution between the voltammetric peaks of hydrochlorothiazide and folic acid which makes it suitable for the detection of hydrochlorothiazide in the presence of folic acid in real samples.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Science and Engineering: C - Volume 52, 1 July 2015, Pages 297-305
نویسندگان
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