کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8131273 | 1523235 | 2018 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Automated Visualization and Quantification of Spiral Artery Blood Flow Entering the First-Trimester Placenta, Using 3-D Power Doppler Ultrasound
ترجمه فارسی عنوان
تجسم اتوماتیک و اندازه گیری جریان خون سرخرگ اسپیرال ورودی به محل قاعدگی اول سه ماهه، با استفاده از سهبعدی سونوگرافی داپلر قدرت
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
آکوستیک و فرا صوت
چکیده انگلیسی
The goal of our research was to quantify the placental vascularity in 3-D at 11-13â+â6âwk of pregnancy at precise distances from the utero-placental interface (UPI) using 3-D power Doppler ultrasound. With this automated image analysis technique, differences in vascularity between normal and pathologic pregnancies may be observed. The algorithm was validated using a computer-generated image phantom and applied retrospectively in 143 patients. The following features from the PD data were recorded: The number of spiral artery jets into the inter-villous space, total geometric and PD area. These were automatically measured at discrete millimeter distances from the UPI. Differences in features were compared with pregnancy outcomes: Pre-eclamptic versus normal, all small-for-gestational age (SGA) to appropriate-for-gestational age (AGA) patients and AGA versus SGA in normotensives (Mann-Whitney). The Benjamini-Hochberg procedure was used (false discovery rate 10%) for multiple comparison testing. Features decreased with increasing distance from the UPI (Kruskal-Wallis test; pâ<0.001). At 2- 3âmm from the UPI, all features were smaller in pre-eclamptic compared with normal patients and for some in SGA compared with AGA patients (pâ<0.05). For AGA versus SGA in normotensive patients, no significant differences were found. Number of jets measured at 2-5âmm from the UPI did not vary because of the position of the placenta in the uterus (ANOVA; pâ>â0.05). This method provides a new in-vivo imaging tool for examining spiral artery development through pregnancy. Size and number of entrances of blood flow into the UPI could potentially be used to identify high-risk pregnancies and may provide a new imaging biomarker for placental insufficiency.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ultrasound in Medicine & Biology - Volume 44, Issue 3, March 2018, Pages 522-531
Journal: Ultrasound in Medicine & Biology - Volume 44, Issue 3, March 2018, Pages 522-531
نویسندگان
Gordon N. Stevenson, J. Alison Noble, Alec W. Welsh, Lawrence Impey, Sally L. Collins,