کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8131395 | 1523237 | 2018 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
High-Frequency Ultrasound Imaging of Tidemark In Vitro in Advanced Knee Osteoarthritis
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
آکوستیک و فرا صوت
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چکیده انگلیسی
High-frequency ultrasound imaging has been widely adopted for assessment of the degenerative changes of articular cartilage in osteoarthritis (OA). Yet, there are few reports on investigating its capability to evaluate subchondral bone. Here, we employed high-frequency ultrasound imaging (25âMHz) to examine in vitro the tidemark in cylindrical osteochondral disks (nâ=â33) harvested from advanced OA knees of humans. We found good correspondence in morphology observed by ultrasound imaging and micro-computed tomography. Ultrasound roughness index (URI) of tidemark was derived from the raw radiofrequency signals to compare with bone quality factors, including bone volume fraction (BV/TV) and bone mineral density (BMD) measured by micro-computed tomography, using the Spearman correlation (Ï). URI of the tidemark was negatively associated with the subchondral plate BV/TV (Ïâ=ââ0.73, pâ<0.001), BMD (Ïâ=ââ0.40, pâ=â0.020), as well as the underneath trabecular bone BV/TV (Ïâ=ââ0.39, pâ=â0.025) and BMD (Ïâ=ââ0.43, pâ=â0.012). In conclusion, this preliminary study demonstrated that morphology measured by high-frequency ultrasound imaging could reflect the quality of the subchondral bone. High-frequency ultrasound is a promising imaging tool to evaluate the changes of the subchondral bone in addition to those of the overlying cartilage in OA.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ultrasound in Medicine & Biology - Volume 44, Issue 1, January 2018, Pages 94-101
Journal: Ultrasound in Medicine & Biology - Volume 44, Issue 1, January 2018, Pages 94-101
نویسندگان
Yan-Ping Huang, Jin Zhong, Jie Chen, Chun-Hoi Yan, Yong-Ping Zheng, Chun-Yi Wen,