Anti-inflammatory effect of avenanthramides via NF-κB pathways in C2C12 skeletal muscle cells

A schematic overview of the role of AVA in inhibiting IκB kinase activity in relation to down-regulation of pro-inflammatory cytokines and the COX-2 / PGE2 pathway. Avenanthramides, Avn; IκB kinase, IKK; Nuclear factor-κB (NF-κB)1, p50; RelA, p65; Cyclooxygenase-2, COX-2; Prostaglandin E2, PGE2. Protein phosphorylation, P.185