کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8289801 | 1536330 | 2015 | 14 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Carotenoids and their conversion products in the control of adipocyte function, adiposity and obesity
ترجمه فارسی عنوان
کاروتنوئیدها و محصولات تبدیل آنها در کنترل عملکرد آدیپوسیت، چاقی و چاقی
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کلمات کلیدی
کاروتنوئیدها، آپوکاروتنوئید، چاقی، چاقی متابولیسم انرژی، قهوه ای بافت چربی سفید،
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
چکیده انگلیسی
A novel perspective of the function of carotenoids and carotenoid-derived products â including, but not restricted to, the retinoids â is emerging in recent years which connects these compounds to the control of adipocyte biology and body fat accumulation, with implications for the management of obesity, diabetes and cardiovascular disease. Cell and animal studies indicate that carotenoids and carotenoids derivatives can reduce adiposity and impact key aspects of adipose tissue biology including adipocyte differentiation, hypertrophy, capacity for fatty acid oxidation and thermogenesis (including browning of white adipose tissue) and secretory function. Epidemiological studies in humans associate higher dietary intakes and serum levels of carotenoids with decreased adiposity. Specifically designed human intervention studies, though still sparse, indicate a beneficial effect of carotenoid supplementation in the accrual of abdominal adiposity. The objective of this review is to summarize recent findings in this area, place them in physiological contexts, and provide likely regulatory schemes whenever possible. The focus will be on the effects of carotenoids as nutritional regulators of adipose tissue biology and both animal and human studies, which support a role of carotenoids and retinoids in the prevention of abdominal adiposity.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Archives of Biochemistry and Biophysics - Volume 572, 15 April 2015, Pages 112-125
Journal: Archives of Biochemistry and Biophysics - Volume 572, 15 April 2015, Pages 112-125
نویسندگان
M. Luisa Bonet, Jose A. Canas, Joan Ribot, Andreu Palou,