Redox reactions of the FAD-containing apoptosis-inducing factor (AIF) with quinoidal xenobiotics: A mechanistic study

► Apoptosis-inducing factor acts as quinone reductase. ► Apoptosis-inducing factor does not contribute to the oxidative stress-type cytotoxicity of quinones. ► Quinones may prevent apoptosis-inducing factor from reductive dimerisation.