3D structure and immunogenicity of Plasmodium falciparum sporozoite induced associated protein peptides as components of fully-protective anti-malarial vaccine

► Native and modified SIAP-1 HABPs have α-helical structures and lengths. ► Changes in HABPs structure enables their fitting into HLA-DRβ1∗ molecules. ► Modified HAPBs could be potential targets in developing antimalarial vaccine.