TRPV1 agonist piperine but not olvanil enhances glutamatergic spontaneous excitatory transmission in rat spinal substantia gelatinosa neurons

► We examined the effect of TRPV1 agonists on synaptic transmission in the CNS. This result was different from that in the PNS. There may be a difference in TRPV1 property between the CNS and PNS.