In vitro brown and “brite”/“beige” adipogenesis: Human cellular models and molecular aspects

► Human adults possess thermogenic BAT whose activation can lead to weight loss. ► White adipocytes can be converted into “brite” (brown-in-white) adipocytes. ► Human cell models are needed to decipher the molecular events of brite formation. ► miRNAs are novel regulators of adipogenesis towards white, brite/brown adipocytes.