Secretagogues of lung surfactant increase annexin A7 localization with ABCA3 in alveolar type II cells

► Specific antibody is used for annexin A7 trafficking in alveolar type II cells. ► Cell-stimulation increased annexin A7 in cell membranes and lamellar bodies. ► Membrane-association or co-localization required protein kinase activation. ► Stimulation increases annexin A7 phosphorylation at serine and threonine residues. ► Phosphorylation of annexin A7 may regulate its function during membrane fusion.